Hypertrophy of Granular Endoplasmic Reticulum and Annulate Lamellae in Earle's L Cells Exposed to Vinblastine Sulfate
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چکیده
منابع مشابه
Binding of Colchicine-3h to Vinblastine- and Vincristine-induced Crystals in Mammalian Tissue Culture Cells
the vinca alkaloids, vinblastine sulfate and vincristine sulfate (Velban and Oncovin, respectively ; Eli Lilly and Co ., Indianapolis, Ind .), cause hypertrophy of the granular endoplasmic reticulum and annulate lamellae in cultured mammalian cells (7), and the accumulation of large proteinaceous cytoplasmic crystals in tissue culture cells (8), in cells of the central nervous system (9), and i...
متن کاملObservations on the Association of Helical Polyribosomes and Filaments with Vincristine-induced Crystals in Earle's L-cell Fibroblasts
Earle's L-929 fibroblasts from cultures treated with 5-10 microg/ml of vincristine sulfate have a large number of eosinophilic, proteinaceous crystals in their cytoplasm. In electron micrographs, large arrays of helical polyribosomes, stacks of Golgi lamellae, and membranes of granular endoplasmic reticulum are seen in the cytoplasm of these cells. "Stalks" of fine granular material, approximat...
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Electron microscope studies were made on various tunicate oocytes at different stages of growth and development. Both the inner and outer lamellae of the perforated nuclear envelope demonstrate considerable blebbing activity. The blebs of the inner lamella detach into the nucleoplasm where they undergo a special type of fusion process resulting in the formation of numerous, usually single, diff...
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This report describes an unusual morphology of annulate lamellae (AL) in the hepatocytes of Torpedo marmorata Risso. These Als and fragments are detected amidst the main glycogen and lipid deposits. AL cisterns are circumscribed by parts of the smooth endoplasmic reticulum. Based on the finding of these unusual annular ALs, accompanied by other subcellular lesions such as a number of membranous...
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The intracellular sites of glycogen degradation in the mid to late uterine chick embryo were determined by cytochemical localization of glucose-6-phosphatase at the ultrastructural level. Enzyme activity was found between the two membranes of the nuclear envelope, in the annulate lamellae and in specialized glycogen-containing membrane scrolls. Annulate lamellae and glycogen scrolls were most f...
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ورودعنوان ژورنال:
- The Journal of Cell Biology
دوره 39 شماره
صفحات -
تاریخ انتشار 1968